Natalie Kegulian, Ph.D.

 

Research Associate
Center for Craniofacial Molecular Biology
Herman Ostrow School of Dentistry of USC

2250 Alcazar St.
CSA 149 – HSC 9062
Los Angeles, CA 90033-9062
Phone: (323) 442-2701
Fax: (323) 442-2981
kegulian@usc.edu

Education
Experience
Publications

University of Southern California, Los Angeles, CA
B.S., 2009
Biological Sciences

University of Southern California, Los Angeles, CA
Ph.D., 2015
Genetic, Molecular & Cellular Biology

  • 2021 – present – Research Associate – Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2018 – 2021 – Postdoctoral Scholar – Fellowship Trainee – Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2018 – 2018 – Postdoctoral Scholar – Research Associate – Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2017 – 2018 – Postdoctoral Scholar – Research Associate – Dornsife College of Letters, Arts, and Sciences, University of Southern California, Los Angeles, CA
  • 2015 – 2017 – Postdoctoral Scholar – Research Associate – Keck School of Medicine, University of Southern California, Los Angeles, CA
  • 2013 – 2013 – Graduate Teaching Assistant – Keck School of Medicine, University of Southern California, Los Angeles, CA
  • 2009 – 2015 – Graduate Research Assistant – Keck School of Medicine, University of Southern California, Los Angeles, CA

  1. Kegulian NC, Langen R, Moradian-Oldak J. The Dynamic Interactions of a Multitargeting Domain in Ameloblastin Protein with Amelogenin and Membrane. International Journal of Molecular Sciences. 2023; 24(4):3484. https://doi.org/10.3390/ijms24043484.

  2. Su J, Kegulian NC, Arun Bapat R, Moradian-Oldak J. (2019) Ameloblastin Binds to Phospholipid Bilayers via a Helix-Forming Motif within the Sequence Encoded by Exon 5. ACS Omega. 2019 Feb 28;4(2):4405-4416. doi: 10.1021/acsomega.8b03582. PubMed PMID: 30873509; PubMed Central PMCID: PMC6410667.

  3. Kegulian NC, Ramms B, Horton S, Trenchevska O, Nedelkov D, Graham MJ, Lee RG, Esko JD, Yassine HN, Gordts PLSM. (2019) ApoC-III Glycoforms Are Differentially Cleared by Hepatic TRL (Triglyceride-Rich Lipoprotein) Receptors. Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):2145-2156. doi: 10.1161/ATVBAHA.119.312723. Epub 2019 Aug 8. PubMed PMID: 31390883; PubMed Central PMCID: PMC6761044.

  4. Bravo-Arredondo JM, Kegulian NC, Schmidt T, Pandey NK, Situ AJ, Ulmer TS, Langen R. (2018) The folding equilibrium of huntingtin exon 1 monomer depends on its polyglutamine tract. J Biol Chem. 2018 Dec 21;293(51):19613-19623. doi: 10.1074/jbc.RA118.004808. Epub 2018 Oct 12. PubMed PMID: 30315108; PubMed Central PMCID: PMC6314148.

  5. Kegulian NC, Sankhagowit S, Apostolidou M, Jayasinghe SA, Malmstadt N, Butler PC, Langen R. (2015) Membrane Curvature-sensing and Curvature-inducing Activity of Islet Amyloid Polypeptide and Its Implications for Membrane Disruption. The Journal of biological chemistry. 2015; 290(43):25782-93. PubMed [journal] PMID: 26283787, PMCID: PMC4646232

  6. Fodale V, Kegulian NC, Verani M, Cariulo C, Azzollini L, Petricca L, Daldin M, Boggio R, Padova A, Kuhn R, Pacifici R, Macdonald D, Schoenfeld RC, Park H, Isas JM, Langen R, Weiss A, Caricasole A. (2014) Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopy. PloS one. 2014; 9(12):e112262. PubMed [journal] PMID: 25464275, PMCID: PMC4251833

  7. Mizuno N, Varkey J, Kegulian NC, Hegde BG, Cheng N, Langen R, Steven AC. (2012) Remodeling of lipid vesicles into cylindrical micelles by α-synuclein in an extended α-helical conformation. The Journal of biological chemistry. 2012; 287(35):29301-11. PubMed [journal] PMID: 22767608, PMCID: PMC3436199