Welcome

The Herman Ostrow School of Dentistry of USC’s Center for Craniofacial Molecular Biology is a unique facility that unites world-class researchers in a variety of disciplines centered around structures of the craniofacial region. Since its inception in 1991, CCMB has been home to several major discoveries and has attracted top researchers from around the world.

June 10, 2021

Keck School of Medicine student, Eloise Stanton ‘23, has been awarded ‘Best Presentation’ at the International Research Conference on Plastic Surgery and Craniofacial Surgery

Keck School of Medicine student, Eloise Stanton ‘23, has been awarded ‘Best Presentation’ at the International Research Conference on Plastic Surgery and Craniofacial Surgery for her presentation on “Gene Mutation and Pharmacological Exposure in Exacerbating Craniosynostosis.” Her research focuses on craniosynostosis, a birth defect that involves premature fusion of cranial sutures, which constricts brain growth and causes an increase in intracranial pressure and deformities to the skull. Eloise’s project is geared towards understanding the development of craniosynostosis through genetics and its interplay with an environmental component, citalopram, a frequently prescribed SSRI (antidepressant) that has been shown to impact the stem cells that are responsible for suture patency.

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March 22, 2021

New publications from Chai Lab

Du J, Jing J, Yuan Y, Feng J, Han X, Chen S, Li X, Peng W, Xu J, Ho T-V, Jiang X, Chai Y.(2021)
Arid1a-Plagl1-Hh Signaling Is Indispensable for Differentiation-associated Cell Cycle Arrest of Tooth Root Progenitors. Cell Reports. 35(1): 108007. doi: 10.1016/j.celrep.2021.108964.

Du J, Jing J, Chen S, Yuan Y, Feng J, Ho T-V, Sehgal P, Xu J, Jiang X, Chai Y.(2021)
Arid1a regulates cell cycle exit of transit-amplifying cells through inhibiting the Aurka-Cdk1 axis in mouse incisor.

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