Mingyi Zhang, Ph.D.

Mingyi Zhang

Postdoctoral Scholar – Fellowship Trainee
Center for Craniofacial Molecular Biology
Herman Ostrow School of Dentistry of USC

2250 Alcazar St.
CSA 115 – HSC 9062
Los Angeles, CA 90033-9062
Phone: (323) 442-2254
Fax: (323) 442-2981
mzhang58@usc.edu

Education
Experience
Publications
Awards

Shandong Agricultural University, China
B.S., 2011
Plant Science

Nanjing Agricultural University, China
M.S, 2014
Cytogenetics

North Dakota State University
Ph.D., 2020
Genomics & Bioinformatics

  • 2023 – present – Postdoctoral Scholar – Fellowship Trainee – Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2021 – 2023 – Postdoctoral Scholar – Research Associate – Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2020 – 2021 – Sequencing Analyst II – QC (Clinical), Aldevron LLC, Fargo, ND
  • 2014 – 2020 – Research Assistant – Department of Plant Science, North Dakota State University, Fargo, ND

  1. Buchanan C, Chen S, Yuan Y, Guo T, Feng J, Zhang M, Carey G, Howard I, Sanchez J, Ho TV, Chai Y. Loss of Runx2 in Gli1+ osteogenic progenitors prevents bone loss following ovariectomy. JBMR Plus, Volume 9, Issue 1, January 2025, ziae141, https://doi.org/10.1093/jbmrpl/ziae141.

  2. Pei F, Guo T, Zhang M, Ma L, Jing J, Feng J, Ho T-V, Wen Q, Chai Y. FGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development. Bone Res 12, 37 (2024). https://doi.org/10.1038/s41413-024-00345-5.

  3. Zhang M, Guo T, Pei F, Feng J, Jing J, Xu J, Yamada T, Ho T-V, Du J, Sehgal P, Chai Y. ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling. Nat Commun 15, 4614 (2024). https://doi.org/10.1038/s41467-024-48285-2.

  4. Guo T, Pei F, Zhang M, Yamada T, Feng J, Jing J, Ho T-V, and Chai Y. Vascular architecture regulates mesenchymal stromal cell heterogeneity via p53-PDGF signaling in the mouse incisor. Cell Stem Cell. 2024 May 03. https://doi.org/10.1016/j.stem.2024.04.011.

  5. Pei F, Ma L, Guo T, Zhang M, Jing J, Wen Q, Feng J, Lei J, He J, Janečková E, Ho TV, Chen JF, Chai Y. Sensory nerve regulates progenitor cells via FGF-SHH axis in tooth root morphogenesis. Development. 2024 Jan 15;151(2):dev202043. doi: 10.1242/dev.202043. Epub 2024 Jan 11. PMID: 38108472.

  6. Zhang M, Feng J, Li Y, Qin PZ, Chai Y. Generation of tamoxifen-inducible Tfap2b-CreERT2 mice using CRISPR-Cas9. Genesis. 2023 Dec 8:e23582. doi: 10.1002/dvg.23582. Epub ahead of print. PMID: 38069547.

  7. Jing J, Zhang M, Guo T, Pei F, Yang Y, and Chai Y. (2022) Rodent incisor as a model to study mesenchymal stem cells in tissue homeostasis and repair. Front. Dent. Med, 30 November 2022, Volume 3 – 2022. https://doi.org/10.3389/fdmed.2022.1068494.

  8. Feng J, Han X, Yuan Y, Cho CK, Janečková E, Guo T, Pareek S, Rahman MS, Zheng B, Bi J, Jing J, Zhang M, Xu J, Ho TV, Chai Y. (2022) TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development. eLife. 2022 Dec 21;11:e80405. doi: 10.7554/eLife.80405. PMID: 36542062; PMCID: PMC9771365.

  9. Zhang M, Zhang W, Zhu X, Sun Q, Chao S, Yan C, Xu SS, Fiedler J, Cai X. (2020) Partitioning and physical mapping of wheat chromosome 3B and its homoeologue 3E in Thinopyrum elongatum by inducing homoeologous recombination. Theor Appl Genet. 2020 Apr;133(4):1277-1289. doi: 10.1007/s00122-020-03547-7. Epub 2020 Jan 22. PMID: 31970450.

  10. Zhang M, Zhang W, Zhu X, Sun Q, Yan C, Xu SS, Fiedler J, Cai X. (2020) Dissection and physical mapping of wheat chromosome 7B by inducing meiotic recombination with its homoeologues in Aegilops speltoides and Thinopyrum elongatum. Theor Appl Genet. 2020 Dec;133(12):3455-3467. doi: 10.1007/s00122-020-03680-3. Epub 2020 Sep 15. PMID: 32930833.

  11. Morris CF, Kiszonas AM, Murray J, Boehm J Jr, Ibba MI, Zhang M and Cai X (2019) Re-evolution of Durum Wheat by Introducing the Hardness and Glu-D1 Loci. Front. Sustain. Food Syst. 3:103. doi: 10.3389/fsufs.2019.00103.

  12. Ibba, M.I., Zhang, M., Cai, X. et al. (2019) Identification of a conserved ph1b-mediated 5DS–5BS crossing over site in soft-kernel durum wheat (Triticum turgidum subsp. durum) lines. Euphytica 215, 200. https://doi.org/10.1007/s10681-019-2518-y.

  13. Zhang W, Zhu X, Zhang M, Shi G, Liu Z, Cai X. (2019) Chromosome engineering-mediated introgression and molecular mapping of novel Aegilops speltoides-derived resistance genes for tan spot and Septoria nodorum blotch diseases in wheat. Theor Appl Genet. 2019 Sep;132(9):2605-2614. doi: 10.1007/s00122-019-03374-5. Epub 2019 Jun 10. PMID: 31183521.

  14. Zhang W, Zhu X, Zhang M, Chao S, Xu S, Cai X. (2018) Meiotic homoeologous recombination-based mapping of wheat chromosome 2B and its homoeologues in Aegilops speltoides and Thinopyrum elongatum. Theor Appl Genet. 2018 Nov;131(11):2381-2395. doi: 10.1007/s00122-018-3160-0. Epub 2018 Aug 14. PMID: 30109393.

  15. Zhang W, Zhang M, Zhu X, Cao Y, Sun Q, Ma G, Chao S, Yan C, Xu SS, Cai X. (2018) Molecular cytogenetic and genomic analyses reveal new insights into the origin of the wheat B genome. Theor Appl Genet. 2018 Feb;131(2):365-375. doi: 10.1007/s00122-017-3007-0. Epub 2017 Nov 1. PMID: 29094182.

  16. Boehm JD, Zhang M, Cai X, Morris CF. (2017) Molecular and Cytogenetic Characterization of the 5DS-5BS Chromosome Translocation Conditioning Soft Kernel Texture in Durum Wheat. Plant Genome. 2017 Nov;10(3). doi:10.3835/plantgenome2017.04.0031. PMID: 29293810.

  17. Zhang W, Cao Y, Zhang M, Zhu X, Ren S, Long Y, Gyawali Y, Chao S, Xu S, Cai X. (2017) Meiotic Homoeologous Recombination‐Based Alien Gene Introgression in the Genomics Era of Wheat. Crop Science. 57(3):1189-1198

  18. Zhang, R., Yao, R., Sun, D. et al. (2017) Development of V chromosome alterations and physical mapping of molecular markers specific to Dasypyrum villosum. Mol Breeding 37, 67 (2017). https://doi.org/10.1007/s11032-017-0671-3.

  19. Zhang R, Hou F, Feng Y, Zhang W, Zhang M, Chen P. (2015) Characterization of a Triticum aestivum-Dasypyrum villosum T2VS·2DL translocation line expressing a longer spike and more kernels traits. Theor Appl Genet. 2015 Dec;128(12):2415-25. doi: 10.1007/s00122-015-2596-8. Epub 2015 Sep 3. PMID:26334547.

  20. Lu Y, Xing L, Xing S, Hu P, Cui C, Zhang M, Xiao J, Wang H, Zhang R, Wang X, Chen P, Cao A. (2015) Characterization of a Putative New Semi-Dominant Reduced Height Gene, Rht_NM9, in Wheat (Triticum aestivum L.). J Genet Genomics. 2015 Dec 20;42(12):685-98. doi: 10.1016/j.jgg.2015.08.007. Epub 2015 Nov 3. PMID:26743986.

  21. Zhang R, Zhang M, Wang X, Chen P. (2014) Introduction of chromosome segment carrying the seed storage protein genes from chromosome 1V of Dasypyrum villosum showed positive effect on bread-making quality of common wheat. Theor Appl Genet. 2014 Mar;127(3):523-33. doi: 10.1007/s00122-013-2244-0. Epub 2014 Jan 10. PMID: 24408374.

  • 2022 – 3rd Place – FaceBase Community Forum Poster Competition