Chen S, Jing J, Yuan Y, Feng J, Han X, Wen Q, Ho TV, Lee C, Chai Y.(2020) Runx2+ niche cells maintain mesenchymal tissue homeostasis through IGF signaling. Cell Reports, Accepted….Continue Reading New publication from Chai lab
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New publication: Modeling microcephaly with cerebral organoids and mice reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly for neural progenitor cell maintenance
We are happy to announce that our manuscript “Modeling microcephaly with cerebral organoids and mice reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly for neural progenitor cell maintenance” has been accepted for publication in Nature Communications!…Continue Reading New publication: Modeling microcephaly with cerebral organoids and mice reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly for neural progenitor cell maintenance
Understanding tooth formation
Polarized odontoblasts (top) and polarized ameloblasts (bottom) forming the initial dentin and enamel during tooth formation. Image from Michael Paine’s lab….Continue Reading Understanding tooth formation
Tissue regeneration
Immune cells govern cell-based tissue regeneration: MicroCT images showed that mesenchymal stem cells (MSC) failed to repair over-sized calvarial defects (center; no treatment, left). However, infusion of regulatory T cells (Treg) significantly improved MSC-based calvarial regeneration (right)….Continue Reading Tissue regeneration
Research Story
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Yang Chai
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Lab Photo
This is where a featured article could be placed. Lorem ipsum dolor sit amet, consectetur adipiscing elit. In id velit diam. Nullam ac justo ligula, id iaculis lorem. Mauris vulputate tristique commodo. Nulla sodales malesuada interdum. Nunc sollicitudin mollis odio vitae rutrum. Nulla rutrum facilisis accumsan. Curabitur ullamcorper pulvinar libero, eu facilisis ipsum aliquet et….Continue Reading Lab Photo