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Micro CT and Micro MRI imaging of a mouse skull, showing hard and soft tissue….Continue Reading Dynamic imaging

Stem cells located near vasculature in the retina. Red: GS-IB4 staining, labeling the endothelium. Green: H2BGFP labeling nuclei derived from neural crest cells. Image from Yang Chai’s lab….Continue Reading Stem cell research

Polished coronal section from a mandibular incisor tooth of a 6-week old transgenic mouse over-expressing dentin sialoprotein in the enamel matrix. The mesial aspect of the tooth is to the top, and the labial aspect is to the right. The junction between the enamel and the underlying dentin (dentino-enamel junction) is clearly evident. Image from…Continue Reading Tooth enamel research

Fluorescence microscopy image of  periodontal ligament stem cells cultured (14 days) on titanium surfaces coated with amelogenin-apatite nano-composite. Image taken by JinPu Chu, Visiting Scholar in Oldak’s group….Continue Reading Biomaterials research

Confocal images of mouse mandibular molars showing immunofluorescence of amelogenin (green) and enamelin (red) at postnatal day 3. Co-localization of amelogenin and enamelin is revealed by overlapping signals resulting in yellow/orange staining. Nuclei are stained with DAPI (blue). Image taken by Postdoctoral Associate Victoria Gallon. Scale is 100 microns….Continue Reading Understanding enamel formation

Whisker pad tissue section. Green: H2BGFP labeling nuclei derived from neural crest cells. Blue: DAPI staining, labeling nuclei of all tissues. Image from Yang Chai’s lab….Continue Reading Stem cell research

SEM image shows the morphology of a newly-grown apatite layer formed in chitosan hydrogel without amelogenin after remineralization in an artificial saliva solution for 7 days. Image from Janet Oldak’s lab….Continue Reading Biomaterials science