Andres Stucky, Ph.D.

Research Associate
Center for Craniofacial Molecular Biology
Herman Ostrow School of Dentistry of USC

2250 Alcazar St.
CSA 140 – HSC 9062
Los Angeles, CA 90033-9062
Phone: (323) 442-2837
Fax: (323) 442-2981
astucky@usc.edu

Education
Experience
Publications

Universidad Nacional de Colombia, Bogota, Colombia
B.A., 2005
Anthropology

City University of New York, New York, NY
M.S., 2008
Neuroscience

City University of New York, New York, NY
Ph.D., 2013
Neuroscience

  • 2022 – present – Research Associate – Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA
  • 2015 – 2021 – Postdoctoral Fellow – Department of Periodontics and Diagnostic Sciences, Ostrow Dental school, University of Southern California, Los Angeles, CA
  • 2014 – – Postdoctoral Fellow – Department of Physiology Pharmacology and Neuroscience, City University of New York, New York

  1. Stucky A, Gao L, Sun L, Li SC, Chen X, Park TH, Cai J, Kabeer MH, Zhang X, Sinha UK, Zhong JF. (2021) Evidence for AJUBA-catenin-CDH4-linked differentiation resistance of mesenchymal stem cells implies tumorigenesis and progression of head and neck squamous cell carcinoma: a single-cell transcriptome approach. Blood Genom. 2021;5(1):29-39. doi: 10.46701/BG.2021012021106. PMID: 34368804; PMCID: PMC8346230.

  2. Liu Q, Hu Y, Stucky A, Fang L, Zhong JF, Wang K. (2020) LongGF: computational algorithm and software tool for fast and accurate detection of gene fusions by long-read transcriptome sequencing. BMC Genomics. 2020 Dec 29;21(Suppl 11):793. doi: 10.1186/s12864-020-07207-4. PMID: 33372596; PMCID: PMC7771079.

  3. Zhong EF, Chang A, Stucky A, Chen X, Mundluru T, Khalifeh M, Sedghizadeh PP. (2020) Genomic Analysis of Oral Lichen Planus and Related Oral Microbiome Pathogens. Pathogens. 2020 Nov 16;9(11):952. doi: 10.3390/pathogens9110952. PMID: 33207582; PMCID: PMC7697643.

  4. Khan A, Liu Q, Chen X, Stucky A, Sedghizadeh PP, Adelpour D, Zhang X, Wang K, Zhong JF. (2019) Detection of human papillomavirus in cases of head and neck squamous cell carcinoma by RNA-seq and VirTect. Mol Oncol. 2019 Apr;13(4):829-839. doi:10.1002/1878-0261.12435. Epub 2019 Feb 23. PMID: 30597724; PMCID: PMC6441885.

  5. Li SC, Stucky A, Chen X, Kabeer MH, Loudon WG, Plant AS, Torno L, Nangia CS, Cai J, Zhang G, Zhong JF. (2018) Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel. Oncotarget. 2018 Sep 7;9(70):33290-33301. doi: 10.18632/oncotarget.26044. PMID: 30279960; PMCID: PMC6161791.

  6. Chen X, Wen Q, Stucky A, Zeng Y, Gao S, Loudon WG, Ho HW, Kabeer MH, Li SC, Zhang X, Zhong JF. (2018) Relapse pathway of glioblastoma revealed by single-cell molecular analysis. Carcinogenesis. 2018 Jul 3;39(7):931-936. doi:10.1093/carcin/bgy052. PMID: 29718126; PMCID: PMC6248540.

  7. Zeng Y, Gao L, Luo X, Chen Y, Kabeer MH, Chen X, Stucky A, Loudon WG, Li SC, Zhang X, Zhong JF. (2018) Microfluidic enrichment of plasma cells improves treatment of multiple myeloma. Mol Oncol. 2018 Jun;12(7):1004-1011. doi:10.1002/1878-0261.12201. Epub 2018 May 12. Erratum in: Mol Oncol. 2021 Jan;15(1):317. PMID: 29638042; PMCID: PMC6026869.

  8. Chen Y, Millstein J, Liu Y, Chen GY, Chen X, Stucky A, Qu C, Fan JB, Chang X, Soleimany A, Wang K, Zhong J, Liu J, Gilliland FD, Li Z, Zhang X, Zhong JF. (2018) Single-Cell Digital Lysates Generated by Phase-Switch Microfluidic Device Reveal Transcriptome Perturbation of Cell Cycle. ACS Nano. 2018 May 22;12(5):4687-4694. doi: 10.1021/acsnano.8b01272. Epub 2018 Apr 18. PMID: 29589910; PMCID:PMC5997256.

  9. Stucky A, Chen X, Zhong JF. (2018) Gene Manipulation with Micro RNAs at Single-Human Cancer Cell. Methods Mol Biol. 2018;1733:215-223. doi:10.1007/978-1-4939-7601-0_18. PMID: 29435936; PMCID: PMC5966013.

  10. Wang HY, Trocmé-Thibierge C, Stucky A, Shah SM, Kvasic J, Khan A, Morain P, Guignot I, Bouguen E, Deschet K, Pueyo M, Mocaer E, Ousset PJ, Vellas B, Kiyasova V. (2017) Increased Aβ42-α7-like nicotinic acetylcholine receptor complex level in lymphocytes is associated with apolipoprotein E4-driven Alzheimer`s disease pathogenesis. Alzheimers Res Ther. 2017 Jul 27;9(1):54. doi:10.1186/s13195-017-0280-8. PMID: 28750690; PMCID: PMC5530996.

  11. Stucky A, Sedghizadeh PP, Mahabady S, Chen X, Zhang C, Zhang G, Zhang X, Zhong JF. (2017) Single-cell genomic analysis of head and neck squamous cell carcinoma. Oncotarget. 2017 May 19;8(42):73208-73218. doi: 10.18632/oncotarget.18021. PMID: 29069864; PMCID: PMC5641207.

  12. Zhang C, Yang SJ, Wen Q, Zhong JF, Chen XL, Stucky A, Press MF, Zhang X. (2017) Human-derived normal mesenchymal stem/stromal cells in anticancer therapies. J Cancer. 2017 Jan 1;8(1):85-96. doi: 10.7150/jca.16792. PMID: 28123601; PMCID:PMC5264043.

  13. Stucky A, Bakshi KP, Friedman E, Wang HY. (2016) Prenatal Cocaine Exposure Upregulates BDNF-TrkB Signaling. PLoS One. 2016 Aug 5;11(8):e0160585. doi:10.1371/journal.pone.0160585. PMID: 27494324; PMCID: PMC4975466.

  14. Li Z, Hao P, Wu Q, Li F, Zhao J, Wu K, Qu C, Chen Y, Li M, Chen X, Stucky A, Zhong J, Li L, Zhong JF. (2016) Genetic mutations associated with metastatic clear cell renal cell carcinoma. Oncotarget. 2016 Mar 29;7(13):16172-9. doi:10.18632/oncotarget.7473. PMID: 26908440; PMCID: PMC4941305.

  15. Zhang C, Zhong JF, Stucky A, Chen XL, Press MF, Zhang X. (2015) Histone acetylation: novel target for the treatment of acute lymphoblastic leukemia. Clin Epigenetics. 2015 Nov 4;7:117. doi: 10.1186/s13148-015-0151-8. PMID: 26543507;PMCID: PMC4634719.

  16. Yang S, Wen Q, Liu Y, Zhang C, Wang M, Chen G, Gong Y, Zhong J, Chen X, Stucky A, Zhong JF, Zhang X. (2015) Increased expression of CX43 on stromal cells promotes leukemia apoptosis. Oncotarget. 2015 Dec 29;6(42):44323-31. doi: 10.18632/oncotarget.6249. PMID: 26517241; PMCID: PMC4792559.

  17. Banerjee A, Wang HY, Borgmann-Winter KE, MacDonald ML, Kaprielian H, Stucky A, Kvasic J, Egbujo C, Ray R, Talbot K, Hemby SE, Siegel SJ, Arnold SE, Sleiman P, Chang X, Hakonarson H, Gur RE, Hahn CG. (2015) Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia. Mol Psychiatry. 2015 Sep;20(9):1091-100. doi:10.1038/mp.2014.115. Epub 2014 Oct 21. PMID: 25330739; PMCID: PMC5156326.

  18. Wang HY, Bakshi K, Frankfurt M, Stucky A, Goberdhan M, Shah SM, Burns LH. (2012) Reducing amyloid-related Alzheimer`s disease pathogenesis by a small molecule targeting filamin A. J Neurosci. 2012 Jul 18;32(29):9773-84. doi:10.1523/JNEUROSCI.0354-12.2012. Erratum in: J Neurosci. 2021 Dec 15;41(50):10405. Erratum in: J Neurosci. 2022 Jan 19;42(3):529. PMID: 22815492; PMCID: PMC6621293.

  19. Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, Arnold SE. (2012) Demonstrated brain insulin resistance in Alzheimer`s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J Clin Invest. 2012 Apr;122(4):1316-38. doi: 10.1172/JCI59903. PMID: 22476197; PMCID: PMC3314463.

  20. Wang HY, Crupi D, Liu J, Stucky A, Cruciata G, Di Rocco A, Friedman E, Quartarone A, Ghilardi MF. (2011) Repetitive transcranial magnetic stimulation enhances BDNF-TrkB signaling in both brain and lymphocyte. J Neurosci. 2011 Jul 27;31(30):11044-54. doi: 10.1523/JNEUROSCI.2125-11.2011. PMID: 21795553; PMCID:PMC3161730.

  21. Bakshi K, Gennaro S, Chan CY, Kosciuk M, Liu J, Stucky A, Trenkner E, Friedman E, Nagele RG, Wang HY. (2009) Prenatal cocaine reduces AMPA receptor synaptic expression through hyperphosphorylation of the synaptic anchoring protein GRIP. J Neurosci. 2009 May 13;29(19):6308-19. doi: 10.1523/JNEUROSCI.5485-08.2009. PMID: 19439608; PMCID: PMC2727739.

  22. Wang HY, Stucky A, Liu J, Shen C, Trocme-Thibierge C, Morain P. (2009) Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer`s disease brain. J Neurosci. 2009 Sep 2;29(35):10961-73. doi: 10.1523/JNEUROSCI.6088-08.2009. Erratum in: J Neurosci.2022 Jan 19;42(3):528. PMID: 19726654; PMCID: PMC6665534.