January 7, 2021
New Publication from Chai Lab
Yu et al., develop a platform for cranial suture regeneration using a biodegradable material combined with mesenchymal stem cells in a mouse model of craniosynostosis that reverses increased intracranial pressure, skull and neurocognitive abnormalities.
Yu M, Ma L, Yuan Y, Ye X, Montagne A, He J, Ho TV, Wu Y, Zhao Z, Sta Maria N, Jacobs R, Urata M, Wang H, Zlokovic BV, Chen JF, Chai Y. (2021) Cranial suture regeneration mitigates skull and neurocognitive defects in craniosynostosis. Cell. 2021 Jan 7; 184 (1): doi: doi.org/10.1016/j.cell.2020.11.037